... Tetrahedron Letters. Volume 44, Issue 37, 8 September 2003, Pages 7091–7094. ... According to a known method, 8 L-Dopa was submitted to Pictet–Spengler reaction using 37% HCHO in 0.5NH 2 SO 4 to yield the 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid 14 ...