Addition of (Pyrazol??1??yl) acetyl and (Pyridin??2??yl) acetyl Groups to the Terminal Amino Group of a Phe− Gly Dipeptide Affords ATCUN??Like Copper (II) Binding Sites

AN Boa, JD Crane, RM Kowalczyk…

Index: Boa, Andrew N.; Crane, Jonathan D.; Kowalczyk, Radoslaw M.; Sultana, Nayer H. European Journal of Inorganic Chemistry, 2005 , # 5 p. 872 - 878

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Citation Number: 4

Abstract

Abstract (Pyrazol-1-yl) acetic acid (HL 1, 1) and (pyridin-2-yl) acetic acid have been successfully condensed with the terminal amino group of a Phe− Gly dipeptide to generate the derivatives PzCH 2–Phe− Gly (H 3 L 2, 7) and PyCH 2–Phe− Gly (H 3 L 3, 8) respectively, which contain ATCUN-like metal ion binding sites. The crystal structures of 1 and the copper (II) complexes Cu (L 1) 2 (H 2 O) 2 (2) and [nBu 4 N][Cu (L 2)](9) are ...