Tetrahedron letters

α-Alkylation of serine with self-reproduction of the center of chirality

D Seebach, JD Aebi

Index: Seebach, Dieter; Aebi, Johannes D. Tetrahedron Letters, 1984 , vol. 25, # 24 p. 2545 - 2548

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Citation Number: 107

Abstract

Abntic. X: The. &&z&m eno&Xe d 06 rn&hyL (ZR, 4SJ-Z-~-blLty~-3-~ ohmy~-oxazo~~ n~-4- c~ boxy~-ate (4b) d&wed &om IS)-(+ I-ntine can be genehated LcLith LVA in THF no. Ction dt-75'C. ALky&&%(+ 9) and hy&oxy&kyMonn[+ E, 111 OCCUIL p~ &~ henti&y(> 95: 51@ om the Re-date 06 the donoh CU&YL (u% u% e topLcAy Lk). Tti hteheochenicaL COUM~ is dehived@ om the abso. Cu* e con&gun_ation 06 2-dtitio- and Z-mtihy1-ntine (~,~ I ...