11 series of S-alkylt, hio-thiated theophy~ hies were prepatred aud screerled filr 1 heir pfiariiiacohgiu nctivily. TIic S-alkylthio-6-thiotheophylline series manifested two types of activity, hot 11 CTS depression and CNS stimulation. The most active CNS depressant, 8- ethylthio-6-thiotheophylli1ie, coniparcd well with thiopeiitd and pentobarbit'al with respect to induction time and sleeping time at equivalent doses in rats. S-(2-N, N-Diethylaminoethyl)- ...
