e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Mercury (II)-mediated cleavage of cyclopropylcarbinols by an intramolecular sulfinyl group as a stereo-and regioselective route to stereotriads and stereotetrads
Mercury (II) salt mediated opening of cyclopropylcarbinols by an intramolecular sulfinyl group is disclosed. All four diastereomeric stereotriads have been prepared from cis-and trans-disubstituted cyclopropanes. The trisubstituted cyclopropanes also react regio-and stereoselectively to afford products possessing quaternary stereogenic centers. The reaction is clean and general.
