Abstract In this study, we report the antimycobacterial and antimicrobial evaluation of newly synthesized 3-(3-pyridyl)-5-(4-methoxyphenyl)-4-(N-substituted-1, 3-benzothiazol-2-amino)- 4H-1, 2, 4-triazole 6a–j in good yields. All the synthesized compounds have been established by elemental analysis, IR, 1 H NMR, 13 C-NMR and Mass spectral data. In-vitro antimycobacterial activity was carried out against (Mycobacterium tuberculosis) H 37 Rv ...