Tetrahedron

Preparation of optically pure (3E, 5E)-alkyl-2-hydroxy-6-arylhexa-3, 5-dienoates by Candida parapsilosis ATCC 7330 mediated deracemisation of the racemates

V Thangavel, A Chadha

Index: Thangavel, Vaijayanthi; Chadha, Anju Tetrahedron, 2007 , vol. 63, # 19 p. 4126 - 4133

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Citation Number: 18

Abstract

As a strategy to prepare optically pure organic molecules, deracemisation 1 and 2 has several advantages over resolution, 3 and 4 especially when a single biocatalyst 5 and 6 can be employed for the purpose. In continuation of our work on Candida parapsilosis ATCC 7330 mediated deracemisation of α- and β-hydroxy esters, 7, 8, 9, 9a, 9b, 10, 11 and 12 we now report here for the first time, the biocatalytic preparation of optically pure (3E,5E)-alkyl-2-hydroxy-6-arylhexa-3,5- ...