A series of novel 1, 2, 3, 5-tetrahydroimidazo [l, 2-a] thieno [2, 3-d]-,-[3, 2-d]-, and-[3, 4-d] pyrimidin-2-one derivatives has been prepared and tested for the activity of inhibiting platelet aggregation in rata in vitro and ex vivo. These compounds were synthesized through the following reactions: sodium borohydride reduction of 2, 4-dichlorothienopyrimidines, followed by ethoxycarbonylmethylation and successive amination. Most of the compounds ...
![[1]Benzothieno[2,3-d]pyrimidine-2,4(1H,3H)-dione,5,6,7,8-tetrahydro- Structure](https://image.chemsrc.com/caspic/237/27285-09-2.png)
![2,4-dichloro-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine Structure](https://image.chemsrc.com/caspic/032/40277-35-8.png)