A simple, rapid, and efficient method for the synthesis of some new thiazolidinone and thiohydantoin derivatives of isatins along with some Mannich bases has been achieved in excellent yield from indole-2, 3-dione-3-thiosemicarbazone employing microwave irradiation.
[Lockman, Jeffrey W.; Reeder, Matthew D.; Robinson, Rosann; Ormonde, Patricia A.; Cimbora, Daniel M.; Williams, Brandi L.; Willardsen, J. Adam Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1724 - 1727]