Simple and Efficient Preparation of Reagents for Thiopyran Introduction: Methyl Tetrahydro-4-oxo-2H-thiopyran-3-carboxylate, Tetrahydro-4H-thiopyran-4-one, and 3, …

DE Ward, MA Rasheed, HM Gillis, GE Beye…

Index: Synthesis, , # 10 p. 1584 - 1586

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Citation Number: 15

Abstract

... Tetrahydro-4 H -thiopyran-4-one (3). Keto ester 2 (100 g, 0.57 mol) was added via a dropping funnel over 3-5 min to a well-stirred solution of 10% aq H 2 SO 4 (1 L) heated under reflux. ... Urben PG. Synthesis 1989, 767; 8d Rule NG. ... J. Chem. 1982, 60: 437; 11d Dowd P. Choi SC. ...