Organic letters

Efficient and Selective Multicomponent Oxidative Coupling of Two Different Aliphatic Primary Amines into Thioamides by Elemental Sulfur

TB Nguyen, L Ermolenko, A Al-Mourabit

Index: Nguyen, Thanh Binh; Ermolenko, Ludmila; Al-Mourabit, Ali Organic Letters, 2012 , vol. 14, # 16 p. 4274 - 4277

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Citation Number: 36

Abstract

The interaction of sulfur with amines has been the subject of several studies.(6-8) McMillan observed the formation of N-benzylthiobenzamide when benzylamine and sulfur were heated together which is, to our knowledge, the only example of such a transformation.(7) In the same report, the reaction has also been applied for an equimolar mixture of benzylamine and morpholine and resulted in a low yield of the corresponding N-(thiobenzoy1)morpholine (40.6%). No ...