Medicinal Chemistry Research

A facile synthesis of new 3, 3-disubstituted phthalides of pharmacological interest

T Chamoli, MSM Rawat

Index: Chamoli, Tanu; Rawat Medicinal Chemistry Research, 2013 , vol. 22, # 1 p. 453 - 465

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Citation Number: 2

Abstract

Abstract A series of new phthalides of pharmacological interest were synthesized by a protocol involving condensation of two γ-keto acids, 2-(4-isopropylbenzoyl) benzoic acid (1a) and 2-(4-isopropyl-3-nitrobenzoyl) benzoic acid (1b) with phenolic compounds in the