Cooperative Catalysis with Aldehydes and Copper: Development and Application in Aerobic Oxidative C H Amination at Room Temperature

Y Xie, B Qian, P Xie, H Huang

Index: Xie, Yinjun; Qian, Bo; Xie, Pan; Huang, Hanmin Advanced Synthesis and Catalysis, 2013 , vol. 355, # 7 p. 1315 - 1322

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Citation Number: 22

Abstract

Abstract A conceptually new cooperative catalytic system via a synergistic combination of aldehyde and copper catalysis has been established based on systemic mechanistic studies. This new cooperative catalysis has been successfully applied in the direct aerobic oxidative C [BOND] H amination of azoles at room temperature, which was previously realized under harsh conditions. Mechanistic studies including isotopic labeling ...