Journal of medicinal chemistry

Potential antileukemic and immunosuppressive drugs. II. Further studies with benzo-2, 1, 3-oxadiazoles (benzofurazans) and their N-oxides (benzofuroxans)

P Ghosh, M Whitehouse

Index: Ghosh,P.B.; Whitehouse,M.W. Journal of Medicinal Chemistry, 1969 , vol. 12, # 3 p. 505 - 507

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Citation Number: 31

Abstract

An earlier paper'described the preparation and in vitro biological activitj of some benzo-2, 1, 3-oxadiazoles (benzofurazans) and their N-oxides (benzofuroxans). Compounds with the 4- nitro substituent were the most potent of those investigated, acting on intracellular and showed some selective action in preferentially inhibiting lymphocytes (potential immunocytes) when tested on a number of animal cells in culture and microorganism^.^ ...