Studies concerning the antibiotic actinonin. Part III. Synthesis of structural analogues of actinonin by the anhydride–imide method

…, BJ Broughton, PJ Warren, KRH Wooldridge…

Index: Devlin; Ollis; Thorpe; Wood; Broughton; Warren; Wooldridge; Wright Journal of the Chemical Society. Perkin transactions 1, 1975 , # 9 p. 830 - 841

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Citation Number: 23

Abstract

A synthetic route, associated with a high degree of stereoselectivity, has been developed for the synthesis of structural analogues (XIII) of actinonin (I). The anhydride–imide method involves the sequence (IIIb)+(V)[(VI)+(VII)](XI)(XIII).(±)-Amino-amides (IIIb) yielded the (±)- hydroxamic acids with the relative c