Identification and optimization of novel Hsp90 inhibitors with tetrahydropyrido [4, 3-d] pyrimidines core through shape-based screening

HP Sun, JM Jia, F Jiang, XL Xu, F Liu, XK Guo…

Index: European Journal of Medicinal Chemistry, , vol. 79, p. 399 - 412

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Citation Number: 13

Abstract

... European Journal of Medicinal Chemistry. ... Nanjing 210009, China; c Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing ... The identification of Hsp90 inhibitors has been attractive for medicinal chemists since the discovery of ...