Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis

HN Bramson, J Corona, ST Davis…

Index: Journal of Medicinal Chemistry, , vol. 44, # 25 p. 4339 - 4358

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Citation Number: 232

Abstract

... Journal of Medicinal Chemistry. ... Chemistry. Isatins and Isatin Hydrazones. Substituted isatins 4 typically were prepared via the classical Sandmeyer reaction 25 involving conversion of the substituted aniline with hydroxylamine ...