Phytochemistry

Pyrone polyketides synthesized by a type III polyketide synthase from Drosophyllum lusitanicum

A Jindaprasert, K Springob, J Schmidt, W De-Eknamkul…

Index: Jindaprasert, Aphacha; Springob, Karin; Schmidt, Juergen; De-Eknamkul, Wanchai; Kutchan, Toni M. Phytochemistry, 2008 , vol. 69, # 18 p. 3043 - 3053

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Citation Number: 18

Abstract

To isolate cDNAs involved in the biosynthesis of acetate-derived naphthoquinones in Drosophyllum lusitanicum, an expressed sequence tag analysis was performed. RNA from callus cultures was used to create a cDNA library from which 2004 expressed sequence tags were generated. One cDNA with similarity to known type III polyketide synthases was isolated as full-length sequence and termed DluHKS. The translated polypeptide ...