Toward the development of a general chiral auxiliary. A total synthesis of (+)-tetronolide via a tandem ketene-trapping [4+ 2] cycloaddition strategy

RK Boeckman, P Shao, ST Wrobleski…

Index: Ye, Wezhen; Liao, Xiugao Synthesis, 1985 , # 10 p. 986 - 988

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Citation Number: 48

Abstract

... 1,4 Subsequently, it was found that tetrocarcin A showed activity against sarcoma 180, P-388 leukemia, and B16 melanoma, as well ... which tetrocarcin A elicited the observed antitumor activity was hypothesized to be inhibition of either DNA or protein synthesis or both. ... 10 figure ...