Chemistry letters

A highly stereoselective knoevenagel reaction of N-tosylimines with active methylene compounds in DMSO

R Chiba, T Oriyama

Index: Chiba, Ryoichi; Oriyama, Takeshi Chemistry Letters, 2008 , vol. 37, # 12 p. 1218 - 1219

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Citation Number: 12

Abstract

In the presence of molecular sieves (MS) 4A in dimethyl sulfoxide (DMSO), a highly stereoselective Knoevenagel reaction of various N-tosylimines with active methylene compounds proceeded smoothly, producing the corresponding Knoevenagel products in high to excellent yields.