Structure–activity studies of 4-phenyl-substituted 2′-benzoylpyridine thiosemicarbazones with potent and selective anti-tumour activity

AY Lukmantara, DS Kalinowski, N Kumar…

Index: Organic and Biomolecular Chemistry, , vol. 11, # 37 p. 6414 - 6425

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Citation Number: 12

Abstract

... 5,10,11 As an important aspect of their mode of action, the iron and ... The chemical structures of 8a and 8i indicate weak intra-molecular H-bonding (Fig ... that a correlation existed between anti-proliferative activity and their capability to undergo Fenton Chemistry upon complexation ...