Indazoles as indole bioisosteres: synthesis and evaluation of the tropanyl ester and amide of indazole-3-carboxylate as antagonists at the serotonin 5HT3 receptor

P Fludzinski, DA Evrard, WE Bloomquist…

Index: Journal of Medicinal Chemistry, , vol. 30, # 9 p. 1535 - 1537

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Citation Number: 74

Abstract

... chemical shift (ppm from Me4Si, in Me2SO) carbon 7 8 3 134.7 125.0 3a 124.2 124.2 4 124.5' 122.3b 5 122.4O 126.2b 6 128.0 127.6b 7 112.1 119.2 7a 142.1 147.9 8 37.7 42.6 9 163.7 161.4 10 53.0 53.4 arbThese assignments may ... Journal of Medicinal Chemistry, 1987, Vol ...