Abstract γ-Tocopherol, a component of the essential nutrient mixture commonly designated as vitamin E, was chemically combined with differently substituted monofluoro-and difluorophenyl moieties to produce potential antagonists for the human aryl hydrocarbon receptor (AhR). 5-Iodo-γ-tocopherol was a very reliable starting material for the Pd-catalyzed reaction with (fluorophenyl) boronic acids (Suzuki coupling). The ortho-and meta-fluoro- ...
