Tetrahedron

Asymmetric synthesis of andavadoic acid via base-catalyzed 5-exo-tet cyclization of a β-hydroperoxy epoxide

B Barnych, B Fenet, JM Vatèle

Index: Tetrahedron, , vol. 69, # 1 p. 334 - 340

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Citation Number: 16

Abstract

... Tetrahedron. Volume 69, Issue 1, 7 January 2013, Pages 334–340. ... To a solution of pentenolide 10 (2.28 g, 6.95 mmol, 1 equiv) in MeOH (100 mL) was added H 2 O 2 (35%, 2.13 mL, 24.3 mmol, 3.5 equiv) and 6 N NaOH (0.7 mL, 4.17 mmol, 0.6 equiv) at 0 °C. After 10 min, a ...