We have been investigating synthetic procedures which would allow us to access a range of phosphonic acid analogues of carbocyclic nucleosides. [5] Herein, we wish to report a flexible synthesis of hydroxy, dihydroxy and dideoxy versions using an efficient epoxide-opening strategy outlined in Scheme [1] . Carbocyclic ribose analogues have been synthesised in a variety of ways, usually starting with ribose itself or a substituted cyclopentane derivative. [6] Such ...
