Regioselective Arene Functionalization: Simple Substitution of Carboxylate by Alkyl Groups

T Krueger, K Vorndran, T Linker

Index: Vorndran, Katja; Linker, Torsten Angewandte Chemie - International Edition, 2003 , vol. 42, # 22 p. 2489 - 2491

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Citation Number: 11

Abstract

Abstract Arenes with various alkyl side-chains were synthesized in high yields and excellent regioselectivities. Starting from toluic and naphthoic acids, the carboxylate group was conveniently substituted by alkyl halides by Birch reduction and subsequent