Practical Asymmetric Synthesis of a Chiral Piperazinone Derivative

M McLaughlin, K Belyk, C Chen, X Linghu…

Index: Organic Process Research and Development, , vol. 17, # 8 p. 1052 - 1060

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Citation Number: 13

Abstract

... Organic Process Research & Development. ... figure Scheme 4. Improved synthesis of cyclic sulfimidate 15. This procedure was deemed unsuitable for large-scale synthesis, and we developed a new ... Since this process is a simple addition reaction, there are no gaseous byproducts ...