Biosynthetic intermediates to the macrocyclic trichothecenes

…, G Pavanasasivam, CE Holmlund…

Index: Jarvis, Bruce B.; Pavanasasivam, Gowsala; Holmlund, C. E.; DeSilva, Tuley; Stahly, G. Patrick; Mazzola, Eugene P. Journal of the American Chemical Society, 1981 , vol. 103, # 2 p. 472 - 474

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Citation Number: 22

Abstract

Two interesting questions about these compounds are (1) what is their role, if any, in the biosynthesis of the macrocyclic trichothecenes and (2) how do the biological activities, especially those associated with the trichoverrins, compare with the bioactivities of the macrocyclic trichothecenes? Here we present data addressing the first question, and we have preliminary data on the second one, which suggest that the bioactivity of the ...