Inhibition of monoamine oxidase types A and B by 2-aryl-4H-1, 3, 4-oxadiazin-5 (6H)-one derivatives

F Mazouz, L Lebreton, R Milcent, C Burstein

Index: Mazouz; Lebreton; Milcent; Burstein European Journal of Medicinal Chemistry, 1988 , vol. 23, # 5 p. 441 - 451

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Citation Number: 29

Abstract

Abstract Monoamine oxidase (MAO) assay specificity based on substrate specificity was investigated by substrate competition experiments. 10 μM serotonin (5-HT) and 5 μM β- phenylethylamine (PEA) were found to ensure total substrate specificity for, respectively, MAO types A and B.