e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Copper-and phosphine-free Sonogashira coupling reactions of aryl iodides catalyzed by an N, N-bis (naphthylideneimino) diethylenetriamine-functionalized …
A polymer-supported palladium (II) N, N-bis (naphthylideneimino) diethylenetriamine complex is found to be a highly active catalyst for Sonogashira coupling reactions. The reactions are performed under copper-and phosphine-free conditions in an air atmosphere. The palladium catalyst is easily separated, and can be reused several times without significant loss in catalytic activity.