Abstract Chiral C 2-symmetric N-benzylazetidines have been conveniently prepared from optically pure anti-1, 3-diols without loss of enantiomeric purity. N-Debenzylation led to the corresponding N-unsubstituted azetidines, which were then subjected to palladium- catalysed coupling reactions with aryl bromides to afford chiral N-arylazetidines.(R, R)-N- Benzyl-2, 4-dimethylazetidine has been employed in the synthesis of a new ...
