Synthetic Communications®

Efficient one-pot synthesis of 2-arylbenzo [b] furans from 2-styrylphenols using CuBr2

S Bhatt, K Roy, SK Nayak

Index: Bhatt, Suchitra; Roy, Kshama; Nayak, Sandip K. Synthetic Communications, 2010 , vol. 40, # 18 p. 2736 - 2746

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Citation Number: 5

Abstract

A new route to the synthesis of 2-arylbenzo [b] furans has been developed. It involves homo/cross-McMurry coupling of salicylaldehyde/substituted salicylaldehydes/aromatic aldehydes to 2-styrylphenols, which undergo intramolecular cyclization with CuBr2 in tetrahydrofuran at ambient temperature to afford 2-arylbenzo [b] furans in good yields.