Hydroruthenation triggered catalytic conversion of dialdehydes and keto aldehydes to lactones

…, T Fukuyama, Y Murakami, H Okamoto, I Ryu

Index: Omura, Sohei; Fukuyama, Takahide; Murakami, Yuji; Okamoto, Hiromi; Ryu, Ilhyong Chemical Communications, 2009 , # 44 p. 6741 - 6743

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Citation Number: 17

Abstract

Lactones are important frameworks found in a variety of biologically active compounds including antibiotics, antifungal compounds, pheromones, lignans, and flavor components. 1 Typically, lactones are prepared by the dehydration reaction of ω-hydroxy carboxylic acids with acid catalyst or stoichiometric coupling reagents such as DCC/DMAP, Mukaiyama–Corey's reagent and Yamaguchi's reagent. 2 On the other hand, the direct conversion of dialdehydes to lactones represents ...