Molecules

Fluorinated analogs of malachite green: synthesis and toxicity

…, M Nilsen-Hamilton, AM Awad, J Banerjee, B Parvin

Index: Kraus, George A.; Jeon, Insik; Nilsen-Hamilton, Marit; Awad, Ahmed M.; Banerjee, Jayeeta; Parvin, Bahram Molecules, 2008 , vol. 13, # 4 p. 986 - 994

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Citation Number: 9

Abstract

Abstract: A series of fluorinated analogs of malachite green (MG) have been synthesized and their toxicity to Saccharomyces cerevisiae and a human ovarian epithelial cell line examined. The toxicity profiles were found to be different for these two species. Two analogs, one with 2, 4-difluoro substitution and the other with 2-fluoro substitution seem to be the most promising analogs because they showed the lowest toxicity to the human ...