Syntheses of 2, 5-and 2, 6-difluoronorepinephrine, 2, 5-difluoroepinephrine, and 2, 6-difluorophenylephrine: effect of disubstitution with fluorine on adrenergic activity

GT Chen, M King, F Gusovsky…

Index: Journal of Medicinal Chemistry, , vol. 36, # 24 p. 3947 - 3955

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Citation Number: 11

Abstract

... 0022-262319311836-3947$04.00/0 0 1993 American Chemical Society Page 2. 3948 Journal of Medicinal Chemistry, 1993, Vol. 36, No. 24 Scheme I F Chen et al. Scheme 11 .O&-= F -$Ho <- 3,4 RO F 2,6-Difluorophenethanol3mines. ...