A Simple and Efficient Process for the Preparation of 1, 6-Dimethoxynaphthalene

T Zhang, Q Yang, H Shi, L Chi

Index: Zhang, Tianyong; Yang, Qiusheng; Shi, Huixian; Chi, Lifeng Organic Process Research and Development, 2009 , vol. 13, # 3 p. 647 - 651

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Abstract

1, 6-Dimethoxynaphthalene (1, 6-DMN) was prepared by the O-dimethylation of 1, 6- dihydroxynaphthalene (1, 6-DHN) with dimethyl sulfate (DMS) in the presence of sodium hydroxide and additives in different solvents. The main reaction determining factors were divided into three categories with respect to yield and purity of 1, 6-DMN:(1) Type of solvents and adding methods of NaOH had the highest effect on the results.(2) Amount of DMS and ...