Asian Journal of Chemistry

Structure Activity Relationship Studies of Some Potent Antifungal Flavones, 4-Thioflavones and 4-Iminoflavones

A Hasan, EU Mughal, A Sadiq

Index: Hasan, Aurangzeb; Mughal; Sadiq Asian Journal of Chemistry, 2012 , vol. 24, # 10 p. 4361 - 4364

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Abstract

Abstract A series of flavones, carrying halogens, methoxy and nitro groups at various positions were synthesized by the Baker-Venkataraman rearrangement and were subsequently converted to 4-thioflavones and 4-iminoflavones. The synthesized compounds were evaluated for their in vitro antifungal activity against Trichophyton longifusus, Candida albicans, Aspergillus flavus, Microsporum canis, Fusarium solani and Candida glabrata. ...