Synthesis of 2??oxo and 2??thioxo??3 (2H)??benzothiazoleethanimic acid anhydride with acetic acid and related products

JJ D'Amico, FG Bellinger…

Index: D'Amico, John J.; Bollinger, Frederic G.; Freeman, John J. Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1503 - 1509

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Citation Number: 16

Abstract

Abstract The reaction of the appropriate 2-benzothiazolinone with 2-chloroacetamide under basic conditions afforded the 2-oxo-3 (2H)-benzothiazolineacetamides 6–9. The 2-thioxo-3 (2H)-benzothiazolineacetamide (10) was prepared by the reaction of 3-(carbethoxymethyl) benzothiazoline-2-thione with ammonium hydroxide. The reaction of acetamides 6–10 with the appropriate anhydride containing a catalytic amount of the sodium salt of the acid ...