This paper describes a method for the preparation of purine analogs using the solid-phase approach. Nucleoside bases were constructed on Merrifield resin by sequential displacement of purine dichloride with amines, and after detachment, the purine analogs were condensed with d, l-ribofuranoside compounds by the Vorbrüggen method. Thereof, l- ribofuranoside was prepared from l-arabinose via the selective oxidation–reduction ...
