1-Methyl-2-phenyl-4-quinolones are naturally occurring alkaloids isolated from the leaves and stems of the plant family Rutaceae. 1 They have drawn considerable interest because of their potent pharmacological activities that include antifungal 1a and antitumor activity, 2 inhibition of acetylcholinesterase (AChE), 3 and antimutagenic effect. 4 Several methods have been developed to synthesize 1-alkyl-2-phenyl-4-quinolones from 2'-substituted ...