Abstract: Stereoselective construction of 1, 2 and 1, 3 amino hydroxyl systems was achieved by the intramolecular trapping of the N-tert-butyldimethylsilyloxycarbonyl species (silyl carbamate) activated by fluoride ion. The reaction of the silyl carbamate with 1, 2-syn mesylate 3 gave the 1, 2-anti cyclic carbamate 7, exclusively, with complete inversion of the original stereochemistry of the leaving group. On the other hand, AgF-or AgF/Pd (II)- ...
