e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis and biological evaluation of substituted benzo [h] cinnolinones and 3H-benzo [6, 7] cyclohepta [1, 2-c] pyridazinones: higher homologs of the …
Several substituted benzo [h] cinnolinones 3 and 3H-benzo [6, 7] cyclohepta [1, 2-c] pyridazinones 4, which were designed as less rigid congeners of 5H-indeno [1, 2-c] pyridazinones 2, were synthesized and tested as antihypertensive, inotropic, antithrombotic, antiinflammatory, and antiulcer agents. While the seven-membered ring derivatives displayed only antithrombotic properties, which were comparable to that of acetylsalicylic ...