Pseudomonic acids A (I) and C (2) are members of a novel class of compounds with antibacterial and antimycoplasmal activity.' The first reported synthesis of racemic pseudomonic acid C involved a key step of coupling the racemic form of the pyranose aldehyde (3) with the ylid derived from the racemic form of the phosphonium salt (4)(Scheme 1). 2 Subsequent approaches to racemic3 pseudomonic acids have been directed ...
