Tetrahedron

A microwave assisted synthesis of benzoxazoles from carboxylic acids

G Nieddu, G Giacomelli

Index: Nieddu, Giammario; Giacomelli, Giampaolo Tetrahedron, 2013 ,  vol. 69,  # 2  p. 791 - 795

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Citation Number: 10

Abstract

A series of various poly-substituted benzoxazoles were synthesized starting from readily available carboxylic acids. The method is based on TCT (cyanuric chloride)/microwave acid activation and it is characterized by mild conditions, allowing for a wide range of starting materials and functionalization of final products.