Study of direction of cyclization of 1??azolil??4??aryl/alkyl??thiosemicarbazides

…, M Dobosz, I Wawrzycka??Gorczyca

Index: Siwek, Agata; Wujec, Monika; Dobosz, Maria; Wawrzycka-Gorczyca, Irena Heteroatom Chemistry, 2010 , vol. 21, # 7 p. 521 - 532

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Citation Number: 10

Abstract

Abstract On a four series of 1-azolil-4-aryl/alkyl-thiosemicabazides, a study on the influence of azole moiety on the capability for intramolecular cyclization and its direction was carried out. It was found that for 4-aryl/alkyl-thiosemicabazides with triazole, imidazole, or pyrrole moiety at N-1 nitrogen atom possible products were only s-triazoles, both in alkaline and acidic medium. Successful dehydrocyclization of 1-azolil-4-aryl/alkyl-thiosemicarbazides ...