European journal of medicinal chemistry

Synthesis and antidepressant activity of arylalkanol-piperidine derivatives as triple reuptake inhibitors

YY Zheng, L Guo, XC Zhen, JQ Li

Index: European Journal of Medicinal Chemistry, , vol. 54, p. 123 - 136

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Citation Number: 8

Abstract

... European Journal of Medicinal Chemistry. ... Briefly, a commercially available aryl ketone 3 with 4-benzylpiperidine derivatives 4 in the presence of paraformaldehyde by the Mannich reaction afforded the intermediate arylalkaneone-piperidine derivatives 5a–j in good yields (71 ...