Rational Design, Green Synthesis, and Initial Evaluation of a Series of Full??Color Tunable Fluorescent Dyes Enabled by the Copper??Catalyzed N??Arylation of 6?? …

L Liang, W Wang, J Wu, F Xu, Y Niu…

Index: Liang, Lei; Wang, Wei; Wu, Jun; Xu, Fengrong; Niu, Yan; Xu, Bo; Xu, Ping Chemistry - A European Journal, 2013 , vol. 19, # 41 p. 13774 - 13782

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Citation Number: 11

Abstract

Abstract There is widespread interest in the application, optimization, and evolution of the transition-metal-catalyzed arylation of N-heteroarenes to discover full-color tunable fluorescent core frameworks. Inspired by the versatile roles of pyridazinone in organic synthesis and medicinal chemistry, herein, we report a simple and efficient copper-catalyzed cross-coupling reaction for the N-functionalization of pyridazinones in neat water. To ...