Biochemistry

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11

…, B Prasad, JD Unadkat, Y Suhara, T Okano…

Index: Suhara, Yoshitomo; Watanabe, Masato; Nakagawa, Kimie; Wada, Akimori; Ito, Yoichi; Takeda, Kazuyoshi; Takahashi, Kazuhiko; Okano, Toshio Journal of Medicinal Chemistry, 2011 , vol. 54, # 12 p. 4269 - 4273

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Citation Number: 25

Abstract

Vitamin K plays an essential role in many biological processes including blood clotting, maintenance of bone health, and inhibition of arterial calcification. A menaquinone form of vitamin K, MK4, is increasingly recognized for its key roles in mitochondrial electron