(1R, 2R)-4, 4-Dimethylpyrazolidine-3, 5-dione-α-d-pyranosyl-2-deoxyriboside

VM Kolb, PA Colloton, PD Robinson…

Index: Kolb, Vera M.; Colloton, Patricia A.; Robinson, Paul D.; Lutfi, Hisham G.; Meyers, Cal Y. Acta Crystallographica Section C: Crystal Structure Communications, 1996 , vol. 52, # 7 p. 1781 - 1784

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Citation Number: 11

Abstract

The first example of a crystalline pyrazolidinedione nucleoside has been synthesized from the reaction of 2-deoxy-d-ribose with 4, 4-dimethylpyrazolidine-3, 5-dione and characterized by X-ray crystallography as a single α-pyranoside diastereomer [IUPAC name: 1-(2-deoxy-α- d-erythro-pentopyranosyl) 1 (R), 2 (R)-4, 4-dimethylpyrazolidine-3, 5-dione, C10H16N2O5]. Although the pyrazolidinedione ring is essentially planar, the two hydrazidic N atoms are ...