Arylaminotetrazole derivatives are synthesized efficiently by the reaction of arylcyanamides and sodium azide in the presence of ZnCl2 under aqueous conditions at reflux. Generally, isomer of 5-arylamino-1H-tetrazole can be obtained from arylcyanamides carrying electron- withdrawing substituent on aryl ring and as the electropositivity of substituent is increased, the product is shifted toward the isomer of 1-aryl-5-amino-1H-tetrazole.
